Uric Acid Nephropathy and Renal Stone Can Cause Renal Failure

Uric acid refers to the catabolite of purine nucleotide. 80% of the purine nucleotide comes from cellular metabolism, and the other 20% derives from daily diet. The uric acid produced from metabolism normally discharges out of human body. High level of uric acid building up in your body without being removed, gout can be occurred.

Renal injuries causing by uric acid can be categorized as three types: chronic uric acid nephropathy, uric acid nephrolithiasis and acute uric acid nephropathy. Different types manifest varying damages.

Symptoms of chronic uric acid nephropathy are backache, frequent urination at night, diuresis and high blood pressure etc. When taking urine test, small amount of proteinuria and blood in urine can be seen.

It is noteworthy that most of the patients with chronic uric acid nephropathy have no symptoms or signs until serious renal damages occur, ESRF (end-stage renal failure) happens in severe cases. High uric acid impairs renal function sharply leading in the occurrence of renal failure.

Patients with high uric acid usually develop gout. They are at higher risks of suffering from renal stones. The higher level your uric acid is, the higher risk the renal stone will develop. Huge renal stone triggers hydronephrosis and causing obstructive nephropathy.

Renal stone can block urinary tract and impair mucosa of urinary tract directly. Consequently, renal stone results in renal failure. That’s why once you have realized your have developed renal stone, the next thing you should do is to see your doctor immediately.

There are several causes of renal failure other than uric acid nephropathy and renal stone; others include glomerulonephritis, high blood pressure, diabetes or massive hemorrhage, dehydration and so on.

Once you have any of the symptoms and signs worry you, you’d better make an appointment with your doctor. Because plenty of causes trigger renal failure, it can be permanent if you don’t take action in the early stage. Any diseases even the small one can lead you to renal failure or ESRF in severe cases. It’s never too late to realize the seriousness of your condition.

More Informations Email Me: kidneyfailurecn@hotmail.com