Top Seven Causes Trigger End-stage Renal Failure

End-stage Renal Failure (ESRF) is the most serious stage of Renal Failure, which cannot be fixed. When the condition develops to ESRF, it denotes that the kidneys quit working completely leading to the excess fluids, wastes and electrolytes build up in human body, one can’t live without dialysis or kidney transplant.

Why would End-stage Renal Failure occur?

There can be a variety of reasons causing ESRF, SLE (systemic lupus erythematosus), allergic purpura, hyperuricaemia and so on.

1. High blood pressure

Evidence shows that 15% of people with high blood pressure would develop to ESRF directly. According to the data from USRDS 2007 Annual Data Report, high blood pressure causes more than 25,000 new cases of kidney failure in the United States. These numbers are frightening and are expected to wildly increasing in the coming ten years.

2. Diabetes

In comparison with hypertension causing ESRF, the number doubles in people with diabetes. With over 20 million people in the United States affected and those numbers on the rise, accounting for nearly 44 percent of new cases.

3. Kidney diseases

All the chronic kidney diseases would lead to ESRF sooner or later. Among them, chronic nephritis becomes a major culprit and glomerulonephritis accounts for 55.7% of cases.

4. Urinary tract infection or obstruction

Chronic pyelonephritis accounts for 21.2% of the cases.

5. Toxic side effects of medications

Research shows that 25% of people with Renal Failure are associated with renal toxic drugs.

6. Age

17.3% elderly people suffer from various kidney diseases in China. Resident patients suffer from urinary tract diseases accounting for 3.4%-6.3% among all the cases. The urinary tract diseases have become the top eight causes of death among elderly people.

7. HIV

HIV has become an increasingly worrisome health problem worldwide, and the new cases of ESRF caused by HIV rises accordingly. Statistics shows that HIV induced ESRF accounts for 1% of ESRF cases. These numbers could surge in recent years as more and more people are infected with HIV.

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