No single causes account for FSGS. Sometimes it can be caused by gene, while in some cases, HIV virus is responsible for the disease. Additionally, some kidney diseases lead to the scarring and then result in the progression of medical condition.
People of any ages and any races can be the candidate of FSGS. One may wonder if the parents get the disease, will their children inherit? More commonly, FSGS is not a genetic kidney disease and won’t pass down to the children. In some cases, however, the disease runs in families. Yet, no good reasons can be unexplained.
Due to FSGS is the most common cause of Nephrotic Syndrome, its signs and symptoms report as heavy proteinuria and swelling etc. Massive albuminuria impairs the charge barrier significantly. Meanwhile, it accelerates the sclerosis of glomeruli and contributes to the worsening of one’s medical condition. No effective treatments are available for patients with Focal Segmental Glomerulosclerosis nowadays. Most commonly, the sufferers will be treated with hormones and blood pressure drugs. Others may respond well to some medications used for suppressing immune system. Those patients’ disease can be treated with routine therapies aforementioned. But for some who do not respond to those therapies, well, they are at a high risk of suffering from Renal Failure in the end. Due to the aggressive progression of FSGS, I strongly suggest those who have no response or little response to the routine therapies to seek further treatments to deal with the problem. Otherwise, it can be just a few years or months for the disease to progress to Chronic Renal Failure (CRF) or End-stage Renal Failure (ESRF). Dialysis and kidney transplant will be inevitable then.
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