High Blood Pressure and Chronic Kidney Failure

Uncontrolled or poorly controlled high blood pressure is the major culprit accounting for the aggravated kidney function. Chronic Kidney Failure may develop as the result of persistent hypertension. How is elevated blood pressure and chronic renal failure or other kidney diseases related? Read on to find your answers.

It is pretty clear that high blood pressure not just is the result of chronic kidney disease, but also the vital influencing factor which takes part in the progression of illness condition. Long-standing as well as poorly controlled hypertension is recognized as an index of poor prognosis of various kidney diseases. Elevated blood pressure threatens Chronic Kidney Failure patients’ life security.
High blood pressure would probably develop in vast majority of ESRD or Chronic Kidney Failure.
Why that would happen and how is these two things associated? Hypertension could lead to renal damages due to vasoconstriction, small blood vessel sclerosis and arteriosclerosis. Furthermore, hyperperfusion, high pressure and high hyperfiltration occur as a result of local elevated blood pressure of glomeruli. What are the results? All those would cause endothelial cells damages of glomerular capillaries, and kidney fibrosis is triggered consequently. Nephrons are damaged, kidney function is injured and kidney function decreases progressively with time. RAAS also takes part in the aggravated illness condition.

RAAS is short for renin-angiotensin aldosterone system, which plays an important role in regulating blood pressure and balancing electrolytes. More precisely, RAAS works for regulating potassium, sodium, blood volume and blood pressure. Therefore, people with progressive Chronic Kidney Failure, especially those with high blood pressure are easily to suffer from RASS dysfunction.