Wednesday, February 20, 2013

How Is Lupus and Renal Failure Associated


Lupus is the abbreviation of SLE (Systemic Lupus Erythematosus). It can affect organs, joints and skin. One of its most serious complications is Renal Failure. Data collected reveals that no less than 40% of adults and 60% of children with lupus will lead to lupus nephritis in the long-run.

The disease is an autoimmune disease, meaning there’s something wrong with one’s immune system resulting in immune dysfunction. In other words, one’s antibodies (defense mechanisms) attack one’s own cells. It can be fatal and causes various complications, such as stroke or Renal Failure. When it affects one’s kidneys, (called lupus nephritis), the antibodies and antigen binds together resulting in immune complexes. Foreign immune complexes deposit on the kidneys and trigger immune reaction. Overactive immune reaction lead to the kidney damages in the end. This is how autoimmune disease occurs.

Lupus shows a tendency to be a hereditary disease, although no specific proof can prove. Here remind those who have a family history of paying more attention to the disease, but it doesn’t mean those who have no family history won’t suffer from the disease.

Hormones and immunosuppressive agents usually are used to deal with the disease. They can help prevent the Lupus Nephritis from progressing to Renal Failure. The treatments, sometimes, don’t work due to some unexplained reasons. What should we do at this time? Obviously, we don’t have time to wait because the disease would progress quickly and lead to Renal Failure or even death. Then for those don’t sensitive to hormones or current drugs, what we should do about that?

Immunotherapy will be just a perfect choice. Immunotherapy, just as its name denotes, treats the disease by dealing with one’s immune system. By adopting Immunotherapy, it corrects one’s overactive immune reaction, stops the combination of antibodies and antigens and then prevents the immune complexes from depositing on the kidneys anymore. What’s more, Immunotherapy works for clearing the immune complexes and corrects the immune system, trains it to kill the bad ones instead of one’s own healthy cells or tissue. Immunotherapy can treat Lupus and Lupus Nephritis from root cause. By treating the disease early, it can help those patients from developing to Renal Failure.

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