How exactly high blood pressure leads to Renal Failure in the end?
Speaking of Renal Failure or ESRF, renal hypertension should be mentioned. Data collected reveals that the Hypertensive Nephropathy brings ESRF or even death to people with this disease. But how exactly does it happen? High blood pressure is more like a disease affecting one’s blood vessels. It blocks one’s arteries and narrows the blood vessels in the whole body, of course, including the blood vessels in kidneys. Consequently, the blood flow to kidneys decreases and also occurs with anoxia. Ischemia and anoxia result in the systemic constriction of blood vessels, and then blood pressure rises accordingly.
The hypertension puts extra stress on the kidneys and damages one’s cells, tissues, renal structure and then triggers the kidney disease. The pathological changes of renal hypertension occur usually in 5-10 years, while the clinical symptoms appear after 10-15 years of suffering from the disease. High blood pressure contributes to the kidney fibrosis and sclerosis and becomes the major culprit of ESRF. What’s worse, even one with mild kidney disease, hypertension speeds up the progression of its development to the Renal Failure or ESRF.
Headache and dizzy are the signs or symptoms of elevated blood pressure, and nausea and vomiting would occur in some serious cases. By those symptoms, you can tell if you have the disease or not. Of course, signs and symptoms won’t be enough, more tests such as imaging studies and biochemical work-up is still needed. Interventional radiologists can accurately diagnose the disease.
Medical management and life-style changes can be adopted to deal with the elevated blood pressure. If one have already had Hypertensive Nephropathy, give your damaged kidneys a break is vital. How? Maybe medications focusing on controlling the blood pressure work. However, find out the underlying causes—high blood pressure means a lot to stop it from progressing to Renal Failure or ESRF.
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