High Creatinine Levels after Kidney Transplantation

Kidney transplantation happens after one’s kidney function is less than 15% left. This stage is called ESRD (End-stage Renal Disease), also known as CKD stage 5. Patients with CKD stage 5 or ESRD have to live with dialysis or kidney transplantation because their kidneys couldn’t function properly. Your new kidney may not work well in your body; the patient may experience high creatinine levels once again.

Patient may wonder why would that happen, and they probably would ask don’t I suppose to get a brand-new kidney, but how to explain these old problems? High creatinine levels, no matter occurs in people with Renal Failure or those after transplant, indicate the decreased kidney function. The elevated creatinine level depends on the cause of kidney dysfunction. Without examining, one cannot comment the possibility. But there are possible following reasons, just for your information.

For those whose Renal Failure or ESRD induced by the primary disease, such as high blood pressure, diabetes, or some autoimmune disease, their raised creatinine level may result from the poorly treated or controlled primary disease.

Well, things change when one has a transplant rejection. This usually happens shortly after the surgery. It is your own immune system recognizes the foreign matter and then attacks it spontaneously. In serious cases, the anti-rejection drugs fail to suppress one’s immune system and lead to transplant failure in the end.

Other reasons accounting for the boosted creatinine level is urologic complication, infection, nephrotoxic drugs or unfavorable internal environment. All those may result in a kidney transplantation failure because the new kidney needs time to get used to the environment but those factors deprive of its right.