Is It Possible to Restore Kidney Function of FSGS

Focal Segmental Glomerulosclerosis (FSGS) is difficult to treat. Majority of patients with this disorder progress to ESRD over 5 to 20 years. In some cases, patients with an aggressive form of FSGS proceed to ESRD in 2 to 3 years. Conventional treatments involve steroids or other immunosuppressive drugs to help relieve the symptoms like Urine Protein. But these therapies fail to restore the overall renal function, so it is wise to find better comprehensive solutions.

FSGS is a kind of autoimmune disease mediated by immune cells. The infiltrating T cells in the glomeruli attack the kidney inherent cells directly or damage the epithelial cells by releasing vascular permeability factors. To treat this disease, we have to firstly control the immune reaction and at the same time remove the immune complex deposited in mesangial region.

For FSGS, the immune complex mainly consists of IgG and C3. This has been identified with series of immune tests. Only if we remove the immune complex deposited in the kidneys and recover the kidney function, can the disease be treated from the root. Otherwise, whenever we stop the steroids, the immune reaction will start again and the disease will relapse.

The fact is that, currently, there is not yet an effective medicine which can help us remove these deposits rapidly. Therefore, immune tolerance is developed to make our body temporarily co-exists with the immune complex so as to stop further inflammatory reaction. Small dose of immune blockers are given regularly to avoid the relapse of the disease. Besides, periodical evaluation of immune reaction in the kidneys can ensure the accuracy of immune blocking.

Immune tolerance is just a interim measure, in the following immune adjustment step, we will begin to remove the immune complex with Chinese medicines including oral medicine, Micro-Chinese Medicine Osmotherapy, and medicated bath.

Chinese medicine for nourishing Qi and blood can be used to strengthen immunity. Moreover, Micro-Chinese Medicine Osmotherapy is another therapy which can function to promote blood circulation and remove blood stasis. Chinese medicine is micronized into one thousandths granules. With the action of the microwave, they can arrive directly at the renal lesions through skin and channels on the back. More important, this remedy can help us activate the self-healing ability of the kidneys and provide necessary nutrients at the same time to speed up the repair of damaged renal cells. Consequently, kidney function of FSGS will get restored over time.