Infection Prevention is The Key to Decrease the Incidence of Nephritis

Nephritis is caused by immunity disturbance. Especially, in most cases of Acute Nephritis, it is resulted from infections, mainly acute streptococcus infection.

Nephritis is a common disease all over the world. Most of them occur after streptococcus infections such as upper respiratory tract infection and impetigo. In the period of scarlatina period, the incidence of Nephritis is higher then the usual days. Although the patients with Acute Nephritis can recover their renal function in a short time, its prognosis in long term is not clear yet. Acute Nephritis is common among the adults. Compared with the child patients, they have poorer prognosis, longer disease process and recover more slowly. In many cases, the diseases progress slowly into Chronic Nephritis or Chronic Renal Failure. Therefore, improving immunity and resistance against infection is the key to prevent Nephritis.

Therefore, all of us should strengthen physical activity so as to improve our immunity. Moreover, changing clothes properly, keeping a good mood, and developing a good daily habit and so on are also can improve our resistance against infections. For the patients with Nephritis, they should be cautious when keep proper amount of exercise based on their own disease condition. In the acute period of the disease, they should mainly stay in bed. In this way, it can decline the burden to both of their heart and kidneys.

Moreover, with the technological development, air-condition, heater and so on improve our life quality so greatly. As we all stay in the unnatural environment, it decreases our resistance against the invasion of virus and bacterium. For example, in the environment of air-condition, the air circulation are sluggish, which is very likely to cause bacterial growth thus leading to infection.
Keeping a good mood plays an important role in improving immunity. Therefore, all the patients with Nephritis should keep optimistic and hold confidence in defeating their disease. Moreover, they should develop a healthy daily habit, having enough sleep, proper diet and so on.

If we can do our best to avoid infection, we will be able to decrease the incidence of Nephritis greatly.

Latent Nephritis: Pathology ,Symptoms, Treatment

Latent Nephritis is also called asymptomatic hematuria and/ or proteinuria. Generally, it is not complicated with swelling, high blood pressure or renal function damage. In most cases, Laten Nephrits is inspected out in physical examination. Most of the patients do not have obvious symptoms or signs. Only a part of the patients have back pain, fatigue, gross hematuria or other typical symptoms.

Pathology of Latent Nephritis

The pathlogical changes in Latent Nephritis are usually mild like mininal change, mild mesangial proliferative glomerular nephritis and focal segmental glomerular nephritisn etc. According to the pathlogical changs, mesangial proliferative glomerular nephritis can be divided into IgA Nephropathy and non-IgA Nephropathy.

Clinical symptoms of Latent Nephritis

Asymptomatic hematuria

Persistent microscopic hematuria and/or frequently occuring gross hematuria are the main clinical sympoms of Latent Nephritis. It mainly occurs among the adults without asymptomatic symptoms and signs. In most of cases of Latent Nephritis, microscopic hematuria is inspected out in physical examination.

The microscopic hematuria featured with persistence and frequent occurrences. A part of the patients may have transient gross hematuria, but it often disappears in a very short time.

Asymptomatic proteinuria

The proteinuria is usually persistent. The amount of urine protein is less than 2g/d mainly albumin. The patients with Latent Nephritis usually are not accompanied by swelling, high blood pressure and the renal function is generally normal. The blood test usually does not show abnormalities. Asymptomatic proteinuria can last for several years. For the patients with hematuria and proteinuria, their prognosis is usually poor that those with hematuria along.

Conventional therapy

1. The patients with Latent Nephritis should take regular tests including urine test, renal function test and high blood pressure test.

2. Protect renal function and avoid the factors that may cause damage to kidneys

3. If the frequnetly occuring tonsillitis is closely associated with hematuria and proteinuria, the patients should take extirpate tonsillitis.

4. For the patients with much proteinuria, they should use ACEI group.

Renal Fibrosis in Chronic Nephritis

Renal fibrosis is a kind of pathological changing process, in which the kidneys are damaged gradually until the kidneys fail completely. Renal fibrosis is an important cause in causing Chronic Nephritis progression.

In Chronic Nephritis, various causes cause renal injury and releasing of inflammatory factors resulting in inflammatory response and enhanced cellar activity. As the renal functional cells get more damage, the cells begin to have phenotypic transformation and ossify and lose function gradually. This is the early stage of renal fibrosis, in which more than half of the renal function still keeps normal so the patients do not present obvious symptoms yet. If the renal fibrosis process is not inhibited effectively, the renal function will keep declining further. When the renal fibrosis approaches to the middle stage, the levels of creatinine, BUN etc will rise obviously. With the progression of renal fibrosis, more and more nephrons lose their normal function. When the residual nephrons are less than 15%, the disease develops into End Stage Renal Failure, namely Uremia. In this stage, nearly all nephrons are ossified. In clinic, the patients will have a series of serious complications like brain disease, heart disease, systemic poisoning symptoms etc.

From the above we can see that if the Chronic Nephritis can not be controlled effectively in its early stage, it will activate the renal fibrosis. Further more, if the renal fibrosis can not be blocked, it will cause the renal function to decline gradually. The key to prevent Renal Failure is to block renal fibrosis.

As the inflammatory response is the primary cause of renal fibrosis, the patients should firstly take relevant treatment to prevent the releasing of the inflammatory factors. In this way, they will be able to prevent Chronic Nephritis from developing into Renal Failure.

Does Nephritis Relapse after a Kidney Transplant

In China, 70 percent end-stage renal disease results from glomerulonephritis. Apart from the hereditary nephritis syndrome, polycystic kidney disease (PKD), chronic nephropyelitis and chronic interstitial glomerulonephritis, almost all types of kidney disease could relapse after a kidney transplant. But there is no need to worry too much. Less than 5 percent transplanted kidneys are lost. Here are the types of kidney disease which are likely to relapse.

FSGS (focal segmental glomerulosclerosis). It has a high relapse rate in people with severe clinical manifestations. Approximate 50 percent will relapse after a kidney transplant.

IgA nephropathy. It has a much higher relapse rate after a kidney transplant. 80 percent patients suffer from the deposition of IgA in the mesangial region. The clinical manifestations are rare and less than 10% transplanted kidneys are lost.

Crescent nephropathy. Although there are successful cases in patients with positive glomerular basement membrane antibody, kidney transplant is performed after the antibody disappears in order to reduce the relapse rate.

Secondary glomerular nephritis. Kidney transplant is performed after all the indicators such as C3 and C4 are normal with small amount of glucocorticoid. Routine biopsy shows that the relapse rate in histology is as high as 35% but the clinical relapse is only 1%. More important, SLE patients are likely to develop phlebothrobosis and arterial thrombus.

Purpura nephritis. It relapse in patients who had the active purpura 8 months before kidney transplant. The relapse rate is as high as 75 percent but the maninfasation relapse rate is low.
Generally, consider it seriously if the relapse rate is higher.

Severe Complications of Acute Glomerulonephritis in Children

Acute Glomerulonephritis is very common in children. The conventional treatments only focus on controlling blood pressure, eradicating infection etc. However, as its underlying cause is not eliminated, Acute Glomerulonephritis will cause a series of severe complications in children.

Hear failure

Heart failure is commonly seen in children with Acute Glomerulonephritis. They often present pulmonary congestion, liver enlargement, left heart failure or right heart failure etc. Also the children can be tested out to have noticeable enlargement of heart. These complications are related to the retention of fluid and sodium due to decreasing in glomerular filtration rate and endocrine abnormality. It usually occurs 1~2 weeks after the onset of Acute Glomerulonephritis.

Cerebropathy

The incidence of cerebropathy in children is 5~10%. The children with Acute Glomerulonephritis usually present headache, vomiting, somnolence. In severe case, they may have coma and convulsions. This may be associated with severe high blood pressure, cerebral edema or cerebrovascular spasm.

Acute Renal Failure

During the acute period of Acute Glomerulonephritis, the mesangial cells and endothelial cells have massive proliferation and even cresent formation, which can cause oliguria and even anuria and Acute Renal Failure.

Although most of the children can recover after proper treatment, some children may progress into Chronic Glomerulonephritis and finally End Stage Renal Failure. Therefore, the parents should not delay the effective treatment for their children.

Treatment for Acute Glomerulonephritis in Children

Acute Glomerulonephritis is very common for children in daily life. For it may develop into several step, parents are worried about children with acute glomerulonephritis. After all, what is acute glomerulonephritis in children? How to treat it?

Acute glomerulonephritis in children

It is very common in children between 3 and 12 years old. Before this disease, children always have pharyngitis, pustulosis scrumpox impetigo, amygdalitis, scarlatina or other infections. During the infection, a large amount of immune complexes (combination of antigen and antibody) have been produced in the blood. So immune complexes have a high risk to deposit in the kidney tissues and arouse a sudden and serious kidney inflammation. So children’s kidneys have been greatly damaged.

Typical symptoms of acute glomerulonephritis in children

When children’s kidney function has been reduced, they often have some symptoms below.

1. Swelling. Children have obvious swelling in eyelids and then the swelling will present in other parts of the body, such as lower limps, back or the whole body.

2. Their blood pressure would rise high or keep normal.

3. Some children have less urine and some have blood in urine. The hematuria presents in pink or deep brown urine.

4. Children would have fever, headache, dizzy, pain on back or fatigue etc.

How to treat acute glomerulonephritis in children?

In our hospital, we adopt the combination of western and Chinese medicine. For western medicine is very effective to remit some symptoms immediately, it is very suitable to put off the acute glomerulonephritis in order to reduce the risk to have other complications. However, it has many side effects for children and may affect their growth. So we use Chinese medicine to remove the side effects of western medicine. Besides, Chinese medicine can promote the kidney tissues rebuilding through providing more blood and oxygen for them. After the comprehensive treatment, children’s illness condition will not relapse and they will keep healthy. In our hospital, Micro-Chinese Medicine Osmotherapy is the evolution of traditional Chinese medicine and can give a better effect.

What is Wrong If I Have an Elevated Creatinine Level

Creatinine refers to a chemical waste product in the blood that passes through the kidneys to be filtered and excrete in urine. The chemical waste is a by-product of normal muscle contractions. People who have chronic kidney disease (CKD) may suffer from high creatinine. So how does this occur?

CKD appear when the kidneys becomes damaged and are no longer able to properly filter waste and extra fluid out of the blood through urine. You will develop raised creatinine levels when the glomerular filtration mechanism becomes gradually damaged.

The higher the level is, the more damage there may be to the kidneys. A level greater than 1.50 mg/dl for male and 1.10 mg/dl for female is abnormal and may indicate kidney disease. For adult patients, dialysis is recommended when the number reach 10.0 mg/dl; for babies with chronic kidney disease, dialysis is recommended when the level is 2.0 mg/dl.

Symptoms of raised creatinine level

Symptoms are the same as Renal Failure symptoms. In some cases, people find out they have kidney failure without feeling any discomforts at all. Yet some persons may experience the following:

▪ Weakness, or fatigue

▪ Confusion

▪ Shortness of breath

▪ Dehydration

As the kidneys becomes increasing unable to cope, your disease will deteriorate. So it is necessary to find an effective treatment to repair the damaged filtration membrane and restore the kidney function so as to avoid dialysis.

As one of the largest kidney disease specialized hospital all over the world, we apply the most advanced immunotherapy, Immunotherapy, and Micro-Chinese Medicine Osmotherapy to help patients treat kidney disease from the root. This is a general introduction, more detailed information is available in our website, or you can consult our online service for free.

The Common Sense of Renal Insufficiency

Renal Insufficiency, also called Renal Failure, is the final result of varieties of progressive kidney diseases. If the kidney diseases can not be brought under control, most of them will develop into Renal Insufficiency. Renal Insufficiency can be subdivided into Chronic Renal Insufficiency and Acute Renal Insufficiency. Acute Renal Insufficiency is often caused by shortage of blood supply in kidneys, renal obstruction or harm of toxin. In contrast, Chronic Renal Insufficiency occurs due to the long-term renal pathological change. As the disease develops, the renal function declines.

There are many causes which lead to Renal Insufficiency including Primary Glomerular Nephritis, Diabetic　Nephropathy, Hypertensive Nephropathy, Renal Interstitial Tubular Nephropathy and PCK (Polycystic Kidney Disease) etc.

In the early stage of Renal Insufficiency, patients with Renal Insufficiency can not feel any symptoms and the only way to find out the renal abnormality is through test. So it is important to take a regular kidney test for people who may be likely to have kidney disease or have family history of kidney disease.

As the disease develops, the toxin in patients’ blood build up so that patients with Renal Insufficiency feel weak, easily get tired and lag in response. As the toxin in blood build up, patients may have symptoms of muscle and nerve system such as muscle weakness, crick and cramp. At this moment, there will be sting-like pain in four extremities and even some parts of body may feel numb. If the blood pressure in patients with Renal Insufficiency is too high and the toxin in blood builds up too much, it may lead to Brain Dysfunction.

Chronic Renal Insufficiency can lead to sexual failure. Statistics shows that about 90% of men with Uremia have problem with sex.

Once people have Renal Insufficiency, they have to treat it timely and effectively with active attitude. For patients with Renal Insufficiency, their kidneys are damaged which lead to the symptoms of Renal Insufficiency. To treat it effectively, we have to restore the damaged renal cells and protect the healthy renal cells. Micro-Chinese Medicine Osmotherapy can restore the damaged renal cells. At the same time, it can provide an easier environment for the further treatment—Immunotherapy. Immunotherapys have the strong self-renewing ability. It means that the Immunotherapy can regenerate a large amount of daughter cells which have the same characteristic as those original Immunotherapy. Then these daughter Immunotherapy can differentiate into renal functional cells to replace the necrotic renal cells. Therefore, the renal function can recover extremely to some extent. Of course, the curative effect depends on the illness condition.

Don't Miss :Lower High Creatinine in Renal Insufficiency

If your want to know more information about Renal Insufficiency and our treatment, please contact us online or send us an email at kidneyfailurecn@hotmail.com.We are glad to help you.

Novel Treatments for Blood in Urine of IgA Nephropathy

IgA Nephropathy, also known as Berger's Disease or IgA Nephritis, is the commonest of a group of conditions called glomerulonephritis. Individuals with IgAN may have varied amount of the IgA sticking in the kidneys due to immune dysfunction, which may cause inflammation and stop the kidneys working properly. The most common symptom of this disease is episodes of blood in urine (haematuria). Is there any novel treatments for this condition?

Treatment for blood in urine of IgAN should be on the basis of an accurate diagnosis through specific tests, such as hematuria localization. This test can help us identify the exact cause of this symptom.

Hematuria localization test

▪ Glomerular hematuria. Flow urinary sediment non-uniformity red blood cells; urinary red blood cells form deformation (red blood cells>75%); ALB/UTP 0.73±0.11.

▪ Non-Glomerular hematuria. Flow urinary sediment uniformity red blood cells; urinary red blood cells form deformation (red blood cells<50%); ALB/UTP 0.41±0.14.

▪ Mixed hematuria. Both non-uniformity and uniformity red blood cells are detected in the urine.
With the above test, we can see whether patient's glomeruli is damaged or not. For patients with glomerular imapirment, the novel therapy -- Immunotherapy can help to repair the kidney damage and rectify the immune dysfunction. Specific treatments of Immunotherapy may involves:

● Micro-Chinese Medicine Osmotherapy, which can clear up the IgA deposits, thus avoiding further glomerular damage. In addition, it can benefit the process of kidney repair.

● Medicated bath. Through the skin the ingredients of herbs can be absorbed into blood, tissues and organs. The body tissues can be regulated and the body's immunity get improved.

● Mai Kang He Ji. This is a special Chinese medicine that can function to replenish vital energy and nourish blood. The immune disorder can be corrected and regulation of immune system gets achieved.

If you are afflicted by recurrent blood in urine of IgAN, you can try our innovative therapy. For more information, you can send an email to kidneyfailurecn@hotmail.com or Contact Online.

FSGS: Lower High Creatinine Level in Natural Ways

The creatinine is the end products of creatine in muscle. Too much consumption of meat can produce more creatinine in blood. Therefore, the patients should limit their daily intake of meat strictly.

Strenuous exercise can accelerate the metabolism of creatine in muscle thus producing more creatine in body. This will inevitably put much strain on kidneys when it is excreted by kidneys. So the patients with FSGS should avoid strenuous exercise and take part in aerobic exercise jogging, bicycling, swimming etc.

Micro-Chinese Medicine Osmotherapy

Micro-Chinese Medicine Osmotherapy can remove creatinine and other metabolic wastes in blood thus lowering high creatinine in FSGS. Meanwhile, it can restore the impaired kidney tissues and recover the excretory function of the kidneys.

① Micro-Chinese Medicine Osmotherapy is an external therapy. When it is performed on body, it can open up pores. A part of toxins in body can be passed out of body through pores.

② The effective medicines can dilate systemic blood vessels and improve microcirculation in kidneys. Therefore, it can boost the excretion of metabolic wastes thus lowering high creatinine level.

③ Micro-Chinese medicine can activate the reproduction of DNA of the impaired renal functional cells, thus restoring the injured kidneys.

Mr. Michael, FSGS kidney disease from America

Name: Michael

Gender: Male

Age: 19

Country: America

Admission time: at 21:00 on Jan. 4, 2012

Discharge time: at 18:00 on Feb. 2, 2012

Admission diagnosis: Focal Segmental Glomerulosclerosis, Chronic Glomerulonephritis, renal insufficiency, Stage 5 CKD, renal anemia, renal hypertension.

Check up before the treatment:

Urine output: 1500mml, Proteinuria: 2+; UPQ: 2.26g/24h; PO4: 1.84mmol/L; Creatinine level in the blood: 780umol/L; BUN: 17.7mmol/l; BMG: 11.5mg/L; Cystatin C: 4.36mg/L; Ccr: 9.51ml/min; Right kidney: 98x52x41mm; Left kidney: 100x50x40mm.

Treatment procedure:

The holistic Immunotherapy was applied to largely improve kidney disease patient's condition:

▪ Immune clearance - clear away the toxic substances that have accumulated in the body;

▪ Our innovative Chinese herbal remedy, Micro-Chinese Medicine is used to block renal fibrosis, avoid more renal damage, and provide an advantageous milieu for the repair of damaged kidney function.

▪ Immunotherapy - repair the damaged renal inherent cells and tissues as well as regulate the immune system of the body.

Check up after the treatment:

Urine output: 1500mml, Proteinuria: 2+; UPQ: 1.95g/24h; PO4: 1.83mmol/L; Serum creatinine: 760umol/L; BUN: 13.1mmol/l; BMG: 13.98mg/L; Cystatin C: 4.21mg/L; Ccr: 9.1ml/min.
After period of treatment with immunotherapy, the interval of kidney dialysis has been prolonged and the life quality gets significantly improved. If FSGS kidney disease patient can continue receiving long-term treatment, the outcome can be even more favorable.

Will UTI Cause High Creatinine in Chronic Kidney Failure

Creatinine is a waste product produced by the muscles through normal contraction. In Chronic Kidney Failure, blood levels of creatinine, metabolic waste products that are normally filtered out by the kidneys, are increased. In some cases, patients may wonder whether urinary tract infection will lead to high creatinine levels in Chronic Renal Failure. Continue reading to find an answer.

For individuals with Chronic Kidney Failure have approximately 3 times greater chance of getting infectious complications, such as UTI. Though kidney dysfunction is the main cause of high creatinine levels, a urinary tract infection may also cause higher levels of creatinine. Moreover, UTI will aggravate the effects of renal failure. So, it is necessary to take effective precautions of UTI as below.

▪ Wear cotton underwear and panty hose with a cotton crotch, as cotton allows air to pass in and out so as to keep the crotch area drier. This is helpful in preventing the flourishing of bacteria in this area.

▪ Females are advised to wipe from front to back. By doing this, we can reduce the risk of bacteria's spreading from anus into the urinary tract.

▪ Urinate before and after sexual intercourse.

▪ Eat some natural diuretics to help flush out the system such as watermelon, parsley, and celery. Besides, take some vitamin C which can help raise the acidity level in the urine, making it harder for bacteria to reproduce.

In western medicine, antibiotics are often used to treat UTI. However, these medicines have their own side effects, such as yeast infections.

Patients have other better choice of natural remedy, such as dandelion. It increases urine flow and the tea made from it flushed the urinary system. Ask our online experts or your doctor about any natural therapy that is suitable for your personalized condition.

Li Xin, FSGS, China

NAME: Li Xin

COUNTRY: Shaanxi Province, China

AGE: 43 years old

GENDER: Female

DIAGNOSIS: Focal Segmental Glomerulosclerosis (FSGS), CKD 4 stage, Renal Hypertension, Renal Anemia

CONDITION BEFORE TREATMENT

Mrs. Li suffered from intermittent swelling legs for five years. She also experienced fatigue as well as abnormal kidney function for 3 months. Her swelling legs appeared with no obvious incentives in 2007. No rash, no joint pains. Li Xin sought for treatment in local hospital and the report showed that her protein urine was 2+, while the occult blood was +. The doctor prescribed her some Chinese medicines and no improvement. Mrs. Li then went to a major hospital in Xi’an City in 2009. According to the renal biopsy, she was diagnosed with FSGS. The main treatment was hormone medications. No therapeutic effect appeared either.

“I came to a hospital specialized in treating kidney disease in Xi’an in August 2009, still no improvements after receiving three-month treatment. I was overwhelmingly depressed and really tired of that.” said Mrs. Li.

The illness condition developed progressively and the lady developed serious fatigue. It was then his serum creatinine was 3.3mg/dL. “This is my last shot. I thought if still no improvement here, then I will quit!”, and that’s how Li Xin came to Kidney Disease Hospital.

START OF TREATMENT: February 19, 2012

TREATMENT FROM  KIDNEY DISEASE HOSPITAL

Micro-Chinese Medicine Osmotherapy, 3 time/day, 45 min/time

Hemofiltration

CONDITION AFTER TREATMENT

After Li Xin hospitalized in  Kidney Disease Hospital, she was received traditional Chinese medicine together with western medicines. The traditional Chinese medicine we used is called Micro-Chinese Medicine Osmotherapy was to deal with kidney fibrosis, while the western medicines mainly focused on treating the symptoms such as fatigue and puffiness.

According with her unique condition, hemofiltration has been adopted to discharge the wastes and toxins building up in her body. The therapy is able to remove the immune complexes.

The fatigue had been greatly relieved, so as her swelling. She could walk as she like and no longer need to stand the poor appetite.

Records before Treatment (February 20, 2012):

Serum creatinine: 3.6mg/dL, urea nitrogen: 12.4mmol/L urea acid: 501umol/l, Bp: 130/90mmHg, protein urine: 2+, occult blood: +, morning urine proportion: 1.008, PH: 5.5, RBC52.40/ul, 24 hr total protein: 2.59g/24hrt, total protein: 58.6g/L, albumin: 35.4g/L, ALT: 5.1U/L, AST:
11.4U/L, hemoglobin: 92g/L

Records after Treatment (March 26, 2012):

Serum creatinine: 2.9mg/dL, urea nitrogen: 9.6mmol/L urea acid: 336umol/l, albumin: 45.6g/L

Know about FSGS (Focal Segmental Glomerulosclerosis)

The cause of Focal Segmental Glomeruloslerosis is still unknown, but affects one’s kidneys seriously. More often than not, FSGS is irreversible in most cases. This is because the disease causes urinary protein loss and eventually would develop scarring of glomeruli. The scarring develops in line with one’s illness condition and this is how they lost their kidney function in the end.

The types of FSGS

Primary and secondary Focal Segmental Glomerulosclerosis are the two types. In primary, the disease could develop as an isolated kidney disease, while in secondary, the disease can be caused by other reasons.

Who is most likely to develop Focal Segmental Glomeruloslerosis?

Well, the disease strikes of all ages. By my experience, the disease attacks more often in black people than white ones, more frequent in men than in women. Apart from these risk factors, drug abuser, people with HIV and AIDS are more likely to suffer from the disease. Obesity, urinary tract infection and other reasons are also responsible for the occurrence of FSGS.

How is it treated?

It is pretty hard for us to treat a patient with unknown kidney disease, because we don’t know what kind of medications we should use. Therefore, most of the treatments for FSGS patients focus on dealing with their symptoms and some of its complications. Pills will be given to help control high blood pressure; diuretics are usually used to remove excess fluid so as to relieve the swelling. What’s more, medications help reduce their protein leakage will be prescribed too.

More specific treatments will be used to treat the disease since it is related to one’s immune system. Immunotherapy, under such circumstance, is right for the disease. We usually adopt blood purification techniques in the first place so as to clear out those immune complexes and other foreign matters. After favorable internal environment is created, then Micro-Chinese Medicine Osmotherapy will be adopted to regulate his own immune system fundamentally. Other treatments are going to be used too. If you are interested, ask our online doctor for details.

Does FSGS Make You Thirsty

FSGS, or Focal Segmental Glomerulosclerosis refers to a condition in which parts of the kidney called glomeruli become scarred. People with FSGS often show no signs or symptoms of the disease unless progressive damage to the kidneys severely interferes with the normal kidney functions. Patients who have massive loss of renal function or Renal Failure will present excessive thirst. How to manage this problem?

When you feel thirsty, you may have a craving or desire to drink something. This is indicated by dryness in the throat and the mouth. Continued parched throat can cause dizziness and giddiness.
Therefore, it is necessary for you to take effective measures to deal with your thirsty. The following are some suggestions, and we hope that they can be helpful for you.

Firstly, restrict the intake of salt, since much salt intake will aggravate your frequency of thirst. Your kidneys have been damaged, so their function of removing fluid is impaired. Drinking much water will increase your risk for getting waster retention, which will aggravate the swelling or edema.

As for the specific amount of water, you are recommended to talk with your doctor or consult our online experts.

Secondly, you are advised to keep away from spicy foods like chilies, curry and hot sauces, etc.
Besides, it is necessary to have a low-protein diet and limit the intake of high-protein foods like beans and bean products. In addition, high potassium foods (like oranges, bananas, tomatoes, potatoes, peanuts), high phosphorus foods (like seafood), and fatty, greasy, and simulating foods (like beef, mutton, crabs, garlic, onions, parsley, wine, coffee, etc) should also be avoided. Stop smoking and drinking alcohol in order to have a better recovery of kidney function.

Alternative Treatments for FSGS Kidney Disease

FSGS Kidney Disease, or Focal Segmental Glomerulosclerosis, is a kind of autoimmune disease. In this disease, the 'glomeruli', the tiny structures which filter the blood, become sclerosed. The general cause is immunological, which means immune dysfunction. Is there any effective therapy to rectify the immune dysfunction?

Nearly 95% of kidneys diseases occur due to abnormal immune system and low immune ability. In this case, the harmful foreign substances cannot be removed after they invade into our body. After combining with antibodies produced by the immune system, immune complex can be formed, which will circulate in the blood and then get deposited in the epithelia of glomeruli. With gradual accumulation of immune complex, our kidneys are damaged. Both the onset and progression of FSGS kidney disease are quick, and many patients will lead to Renal Failure during some years.

In 2012, the latest treatment for FSGS kidney disease is Immunotherapy. This systemic treatment include 6 steps, and several of them can be selected according to your individual illness.

1. An accurate diagnosis. Our hospital has brought the most advanced diagnostic technology and techniques, so we can make a systemic and comprehensive diagnosis of your current condition, and then adopt individual treatment.

2. Immune blocking. Deposits of immune complex will cause series of excess immune reaction, so in this step, exact dose of brand new immunosuppressive agents are used to inhibit the undue inflammation rapidly with no side effects.

3. Immune tolerance. So far, there is no effective medicines that can eliminate the immune complexes. It is necessary to make our body to co-exist with them temporarily with no further inflammatory response.

4. Immune regulation. Micro-Chinese Medicine Osmotherapy is utilised to promote the blood circulation, degrade the immune complex, and then remove them out the body. Moreover, Chinese prescription can be taken to improve the overall immunity.

5. Immune protection. Integrated Chinese - western medicines including glucocorticoid, orally taking Chinese medicine, and Immunotherapy are applied to repair the damaged kidneys and recover the renal functions.

6. Immune clearance. Advanced techniques such as immunoadsorption, plasma exchange and blood purification can help us eliminate the harmful substances in the blood completely.

This is a general introduction of immunotherapy. Is there still anything unclear? Please consult our online service.

Is It Possible to Restore Kidney Function of FSGS

Focal Segmental Glomerulosclerosis (FSGS) is difficult to treat. Majority of patients with this disorder progress to ESRD over 5 to 20 years. In some cases, patients with an aggressive form of FSGS proceed to ESRD in 2 to 3 years. Conventional treatments involve steroids or other immunosuppressive drugs to help relieve the symptoms like Urine Protein. But these therapies fail to restore the overall renal function, so it is wise to find better comprehensive solutions.

FSGS is a kind of autoimmune disease mediated by immune cells. The infiltrating T cells in the glomeruli attack the kidney inherent cells directly or damage the epithelial cells by releasing vascular permeability factors. To treat this disease, we have to firstly control the immune reaction and at the same time remove the immune complex deposited in mesangial region.

For FSGS, the immune complex mainly consists of IgG and C3. This has been identified with series of immune tests. Only if we remove the immune complex deposited in the kidneys and recover the kidney function, can the disease be treated from the root. Otherwise, whenever we stop the steroids, the immune reaction will start again and the disease will relapse.

The fact is that, currently, there is not yet an effective medicine which can help us remove these deposits rapidly. Therefore, immune tolerance is developed to make our body temporarily co-exists with the immune complex so as to stop further inflammatory reaction. Small dose of immune blockers are given regularly to avoid the relapse of the disease. Besides, periodical evaluation of immune reaction in the kidneys can ensure the accuracy of immune blocking.

Immune tolerance is just a interim measure, in the following immune adjustment step, we will begin to remove the immune complex with Chinese medicines including oral medicine, Micro-Chinese Medicine Osmotherapy, and medicated bath.

Chinese medicine for nourishing Qi and blood can be used to strengthen immunity. Moreover, Micro-Chinese Medicine Osmotherapy is another therapy which can function to promote blood circulation and remove blood stasis. Chinese medicine is micronized into one thousandths granules. With the action of the microwave, they can arrive directly at the renal lesions through skin and channels on the back. More important, this remedy can help us activate the self-healing ability of the kidneys and provide necessary nutrients at the same time to speed up the repair of damaged renal cells. Consequently, kidney function of FSGS will get restored over time.

FSGS: Is It an Immunological Disease

More than 95% of kidney diseases are immunological disease and FSGS is not an exception. In order to give suitable treatment, the diagnosis like this judgment is very important. So for patients with FSGS, treatment should focus on immune regulation in order to achieve a good effect.

Overview of FSGS

It is short for focal segmental glomerulosclerosis that means some sections of kidney filters are scarred. After reading this explanation, you can know the general situation about this disease. How does FSGS associate with immunological disease?

Due to unhealthy diet or life style, their immune system is out of order and patients’ immunity is lower than before. In this physical condition, people are very easy to suffer diseases, such as infections or a cold. If their innate immune system is good, immune complexes formed during infections will be removed by immune cells. However, in patients with FSGS, the immune
complexes have to stay in body and would arouse renal failure once they deposit in kidney tissues.

Inflammatory mediators will accumulate around immune complexes in kidney tissues in order to remove them. However, this inflammation will hurt kidney tissues meanwhile. When kidney cells are damaged, the filtering ability cannot be done normally. Many valuable substances in the blood will be leaked from the blood. Furthermore, over time the kidney filters would be scarring and cause loss of kidney function. Once they lose about 50%, FSGS is coming.

Immunotherapy is the correct treatment for immunological disease—FSGS. It mainly contains Immunodepression, immune regulation and immune protection.

Immunodepression will give patients some immunosuppressive agents to restrain renal inflammation in order to protect kidney cells. Furthermore, these agents are regularly needed to keep a good situation in kidneys. However, kidney cannot tolerate immune complexes for a long time. Immune regulation is essential to turn immune system to normal so as to block renal inflammation from the root. If the kidney has a serious hurt, immune protection is provided. It adopts Immunotherapy which does not only provide new kidney cells but also rebuild a new immune system to keep healthy for a long time.

FSGS is Chronic Nephritis in Kidney

Many people are not familiar with FSGS and they know nothing about FSGS but a type of nephritis. It is the abbreviation of focal segmental glomerulosclerosis which is very common in children and adult. In order to treat FSGS, we must know its own characteristics and which treatment is suitable for it.

What is FSGS after all?

Kidney is the main organ to filter the blood and form urine. How to achieve that? In kidneys, there are more than two million glomeruli which are like numerous griddles to help kidney to filter blood. If most of the glomeruli are health, kidneys can function well. So the end waste products and excessive water can be discharged through the filtration of griddles.

However, FSGS means that less than 50% of glomeruli have been destroyed, which is a kind of nephritis. Besides, many kidney tissues have been dead and turned into scars in kidneys. The scars seem that on the skin. There will be no blood or oxygen supplied to the scars. So most part of kidneys has no blood vessels and cannot form urine. In this way, many toxic substances cannot be removed from the body.

What are the common symptoms of FSGS?

FSGS is considered as a type of nephritis which often occurs in children and young people. And males have more risk to suffer FSGS than females. More than two thirds patients have a large amount of proteinuria and severe swelling. Their 24 hours proteinuria is between 1g to 30g. While, more than 50% of patients have hematuria and microscopic hematuria presents in most cases. FSGS develops very quickly and usually patients would go into renal failure or ESRF in one or two years. So patients should receive an effective treatment in the early stage in order to prevent the serious condition.

Why Creatinine Matters and What to Do about That

People with Renal Failure or ESRD live with high levels of creatinine. Elevated creatinine appears almost exclusively in people with the disease. Those patients are told that their creatinine level are dangerously high but don’t know what does that means or affects. If you are really a truth digger, then this may be the right article for you.

Creatinine is the metabolic product stemming from the muscle metabolism. It is excreted by kidneys exclusively, that’s why creatinine becomes the detection marker of kidney damages. A serum creatinine test can tell you how well your kidneys function, while a creatinine urine test measures the creatinine in your urine.

Ostensibly, the reason why creatinine would increase is due to malfunctioned kidneys failing to excrete urine. Substantially, it is caused by kidney fibrosis. The kidney fibrosis results from the occurrence of phenotype transformation as a result of damaged renal intrinsic cells. Fibroblasts change myofibroblasts on account of the stimulation of changes mentioned before. Meanwhile, healthy renal tissues are impaired and develop pathological changes. Consequently, Renal Failure appears in the end.

Due to the progressive damages of kidneys, one’s kidney function decreases accordingly. Of course, the excretory function declines and results in elevated creatinine. Moreover, other indexes such as serum creatinine and urea nitrogen rise too. High blood pressure and swelling attack in most of the patients with Renal Failure or kidney diseases.

After realizing how creatinine increases, you must want to know how to lower high levels of creatinine?

Some may already get the point that lowering the creatinine shouldn’t be the ultimate goal, compared with improving one’s kidney function, decreasing the high levels of creatinine should only be secondary. Because decreased kidney function or malfunctioned kidneys are the major culprits accounting for high levels of creatinine.